Pharmacy Tutorial

1.Indian Medical Association writes to PM Narendra Modi on Ramdev statement. The Indian Medical Association appeal to PM Narendra Modi to take strict action against Ramdev over his statement questioning the efficacy of Allopathy drugs and Doctors. 2.Zydus Cadilla and TLC Ink Pact to market Liposomal Amphotericin B. Zydus Cadilla and Taiwan based Pharma firm TLC have signed an agreement to market Liposomal Amphotericin B, a drug for treatment of Mucormycosis. 3.VAV Life Sciences to increase lipid production for black fungus drug. VAV Life Sciences is ramping up production of crucial lipid ingredients used in making Liposomal Amphotericin B. 4.Our Covid Vaccine highly effective Pfizer to Govt. Pfizer has told Indian Govt.that vaccine has shown high effectiveness against SARS-COV-2 varriant prevalent in India. While suitable for everyone age 12 yrs or above and stored for month 2-8 degree Celsius temperature. 5.20 Crore dose give...

PHARMA UPDATES ⚕️ 1. Recovery rate of 14 states now 90 % or above. 14 states and union Territories have reached a Covid recovery rate of 90 % and above. The highest recovery rate is in Delhi at 97% followed by Uttar Pradesh, Bihar and Haryana at 94% each. 2.IQVIA Biotech announces expansion in Asia Pacific and Japan. IQVIA Biotech announced the expansion in Japan and Asia Pacific (JAPAC) a tailored approach to delivering integrated Clinical and commercial solutions for biotech and emerging biopharma companies. 3. Bal Pharma launches Favipiravir formulation. An Anti viral drug is named as BALflu. The drug made is for the treatment of mild to moderate Covid Infection in patients.  4.The third Booster dose, after it gets Cleared by the authorities, would be administered to the beneficiaries Six months after they get the  second dose of covaxin. 5.I2Cure Bioshield was 97% effective against Sars-Cov 2. The Center for cellu...

"PHARMA UPDATES"⚕️ 1. Panacea Bio-Tech start Production of Sputnik- V Vaccine. The first Batch Produced by companies facility in Baddi Will be transported to the Gamaleya Center in Russia for Quality Control. 2. 'Not Convinced' Covid 19 developed naturally, says Dr. Fauci. Dr. Fauci Anthony  is not convinced  that the novel corona virus developed naturally and has called for an investigation. 3. Cadilla launches drug for Breast Cancer. Zydus Cadilla Launched Ujvira, a drug used for Breast Cancer treatment. The price of drug is ₹32495.  4. North East of India may be next Covid Hotspot. According to development data lab, the North East region of India is likely to be the next victim Of Covid Second wave. 5.Govt. enable on site registration for 18 to 44 age group. The facility is available For Govt. run vaccination centers, Pvt centers will have to publish their vaccination schedule exclusively With slots for online reg...

Amphotericin B (AMB) It is obtained from streptomyces nodosus. #MOA:- The polyene antibiotic molecule is a macrocyclic ring, one side of which has several conjugated double bonds and highly lipophilic, while other side hydrophilic with many OH groups.All polyenes are insoluble in water and unstable in aqueous medium. They have high affinity for ergosterol present in fungal cell membrane.They combine with it get inserted into membrane and several polyene molecules together Orient themselves in such way to form a 'micropore' The hydrophilic side forms interior of pore through which ions, amino acids and other water soluble substances move out. Micropore stabilized by membrane sterols which fill up spaces b/w Amphotericin B molecules on lipophilic side constituting outer surface of pore. Thus cell permeability is markedly increase. Cholesterol present in host cell membrane, closely resembles ergosterol the polyene bind to cholesterol as well through with lesser affinit...